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HUTCHMED Reports Positive Phase III SAFFRON Results for ORPATHYS Plus TAGRISSO in EGFR-Mutated NSCLC

HUTCHMED announced positive results from the SAFFRON Phase III trial for ORPATHYS® (savolitinib) plus TAGRISSO® (osimertinib) in EGFR-mutated non-small cell lung cancer (NSCLC) patients with MET overexpression or amplification. The combination significantly improved progression-free and overall survival compared to platinum-based chemotherapy. These results mark the first global Phase III trial to show such benefits in this patient population, addressing a significant unmet need and supporting global regulatory approvals.

Source: Quiver Quantitative
August 16, 2026 | 23:40:23
Category: General

After TAGRISSO, 338 lung-cancer patients tested a combination—what happened?

HUTCHMED's global Phase III SAFFRON trial showed that ORPATHYS® plus TAGRISSO® significantly improved progression-free and overall survival in patients with MET-driven EGFR-mutated advanced NSCLC after their disease progressed on TAGRISSO®. The combination's safety profile was consistent with known profiles of each medicine, with no new safety findings. These positive results support potential global registrations for the ORPATHYS® plus TAGRISSO® regimen, addressing an unmet need for biomarker-directed treatment options in this patient population.

Source: Stock Titan
August 16, 2026 | 23:40:23
Category: General

Better Value ETF: Vanguard's Small Cap-Focused VBR vs. the iShares IJJ Targeting Mid-Cap Stocks

This article compares two value-focused ETFs: Vanguard's Small-Cap Value ETF (VBR) and iShares' S&P Mid-Cap 400 Value ETF (IJJ). VBR is highlighted for its lower expense ratio (0.05%), higher dividend yield (1.7%), broader diversification with 841 holdings, and stronger one-year and five-year returns, despite higher volatility. IJJ targets mid-cap stocks, offering more stability but with a higher expense ratio (0.18%) and lower returns.

Source: The Motley Fool
August 16, 2026 | 23:41:35
Category: General

ETFs Investing in Globe Life Inc. Stocks

This article lists various Exchange Traded Funds (ETFs) that hold stocks of Globe Life Inc., providing details such as market value, weight, issuer, management style, expense ratio, and 3-year NAV total return for each fund. The funds aim to make investing in stocks more accessible and offer diversified opportunities at lower risk.

Source: TradingView
August 17, 2026 | 00:37:58
Category: General

Uber Sells Serve Robotics Stake, Catches Company Off Guard: ‘Differing Views’ Sour Partnership

Uber has sold its entire stake in autonomous delivery robot company Serve Robotics, a move that reportedly caught Serve Robotics off guard. The partnership, which included up to 2,000 robots for Uber's app, has been strained due to "differing views" on their shared autonomous fleet and is not expected to be renewed after 2027. Serve Robotics also lowered its 2026 revenue outlook significantly, citing lower-than-expected delivery volume through the Uber Eats partnership.

Source: Yahoo Finance
August 17, 2026 | 01:09:16
Category: General

Capital One Financial: Solid 7% Yield From Series I Preferred Shares

Capital One Financial (COF) offers five preferred shares, with the Series I preferred shares providing a solid 7% yield. The company's recent acquisition of Discover Financial has been well-integrated, contributing to stable net interest income and strong loan growth. With low nonperforming assets and robust credit loss coverage, the sustainability of the preferred dividend appears well-supported.

Source: Seeking Alpha
August 17, 2026 | 02:07:35
Category: General

Coca-Cola doubles down on localisation in China as sales grow

Coca-Cola is enhancing its market presence in China through a strategy of hyper-localisation, which includes tailored product innovations, digital engagement, and community initiatives. This approach has contributed to an 8% unit case volume growth across Asia Pacific in Q2, with China being a significant contributor. The company is focusing on gut health products, culturally relevant experiences, and strengthening its local supply chain to deepen consumer connections and investment in the region.

Source: FoodNavigator.com
August 17, 2026 | 02:35:24
Category: General

Block, Inc. Director Anthony Eisen Sells 18,000 Class A Common Stock Shares

Block, Inc. director Anthony Eisen sold 18,000 shares of Class A Common Stock across three trading days in August 2026, as reported in a Statement of Changes in Beneficial Ownership. These sales, executed on August 12, 13, and 14, 2026, were part of a Rule 10b5-1 trading plan adopted on March 2, 2026. Following these transactions, Eisen directly holds 1,524,672 Class A Common Stock shares.

Source: Kalkine
August 17, 2026 | 02:43:28
Category: General

James Hardie Industries Issues 141,354 Unquoted Ordinary Shares Linked to AZEK Merger Equity Awards

James Hardie Industries PLC (ASX:JHX) has announced the issuance of 141,354 unquoted ordinary shares (JHXAM) at USD 0.6806 per share. These shares are part of the settlement for equity awards related to its merger with The AZEK Company Inc., which was finalized on July 1, 2025. The shares are not intended for quotation on the ASX, and James Hardie secured a waiver from ASX Listing Rule 2.4 for this issuance.

Source: Kalkine
August 17, 2026 | 02:44:17
Category: General

T. Rowe Price Associates Discloses 7.4% Stake in Block Inc via Schedule 13G/A Filing

T. Rowe Price Associates, Inc. has disclosed a 7.4% beneficial ownership stake in Block Inc, totaling 39,734,450 shares of common stock, through an amended Schedule 13G/A filing. The investment adviser holds sole voting power over 38,251,704 shares and sole dispositive power over all 39,734,450 shares. This filing, made on August 14, 2026, pertains to an event that occurred on June 30, 2026.

Source: Kalkine
August 17, 2026 | 02:45:13
Category: General

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